F-carbocyclic-AZT
TL;DR: F-carbocyclic-AZT (CAS 127530-13-6) is a chemical compound with molecular formula C11H14FN5O3 and molecular weight 283.10806 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(1S,2S,3S,4S)-4-azido-2-fluoro-3-(hydroxymethyl)cyclopentyl]-5-methylpyrimidine-2,4-dione
Also Known As: F-carbocyclic-AZT, 6'-alpha-Fluorocarbocyclic AZT, 6'-.alpha.-Fluorocarbocyclic AZT, 1-[(1S,2S,3S,4S)-4-azido-2-fluoro-3-(hydroxymethyl)cyclopentyl]-5-methylpyrimidine-2,4-dione, 2,4(1H,3H)-Pyrimidinedione, 1-(4-azido-2-fluoro-3-(hydroxymethyl)cyclopentyl)-5-methyl-, (1alpha,2beta,3alpha,4beta)-
Technical Specifications
| Molecular Formula | C11H14FN5O3 |
| Molecular Weight | 283.10806 g/mol |
| XLogP | 0.7 |
| Topological Polar Surface Area (TPSA) | 84.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 3 |
| Exact Mass | 283.10806 Da |
| Heavy Atoms | 20 |
| Complexity | 516.0 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H]([C@@H]2F)CO)N=[N+]=[N-] |
| InChIKey | HTMVXNVHLREVGF-XGEHTFHBSA-N |
Chemical Property Profile of F-carbocyclic-AZT
Property Insights of F-carbocyclic-AZT
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for F-carbocyclic-AZT. The TPSA of 84.0 Ų falls within the moderate polarity range, balancing permeability and solubility for F-carbocyclic-AZT. Following Lipinski's Rule of Five, F-carbocyclic-AZT has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of F-carbocyclic-AZT?
The CAS number of F-carbocyclic-AZT is 127530-13-6.
What is the molecular formula of F-carbocyclic-AZT?
The molecular formula of F-carbocyclic-AZT is C11H14FN5O3.
What is the molecular weight of F-carbocyclic-AZT?
The molecular weight of F-carbocyclic-AZT is 283.10806 g/mol.
Where can I buy F-carbocyclic-AZT?
You can request a quote for F-carbocyclic-AZT directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for F-carbocyclic-AZT?
Yes, CoreyChem provides custom synthesis services for F-carbocyclic-AZT and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.