Pregnanolone
TL;DR: Pregnanolone (CAS 128-20-1) is a chemical compound with molecular formula C21H34O2 and molecular weight 318.2559 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(3R,5R,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
Also Known As: Pregnanolone, Eltanolona, Eltanolonum, Pregnanolone II, Allopregnanolone
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H34O2 |
| Molecular Weight | 318.2559 g/mol |
| XLogP | 4.9 |
| Topological Polar Surface Area (TPSA) | 37.3 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 318.2559 Da |
| Heavy Atoms | 23 |
| Complexity | 500.0 |
| SMILES | CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)C |
| InChIKey | AURFZBICLPNKBZ-YZRLXODZSA-N |
Chemical Property Profile of Pregnanolone
Property Insights of Pregnanolone
The XLogP value of 4.9 indicates that Pregnanolone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 37.3 Ų, Pregnanolone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Pregnanolone has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Pregnanolone?
The CAS number of Pregnanolone is 128-20-1.
What is the molecular formula of Pregnanolone?
The molecular formula of Pregnanolone is C21H34O2.
What is the molecular weight of Pregnanolone?
The molecular weight of Pregnanolone is 318.2559 g/mol.
Where can I buy Pregnanolone?
You can request a quote for Pregnanolone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Pregnanolone?
Yes, CoreyChem provides custom synthesis services for Pregnanolone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.