Tenofovir disoproxil
TL;DR: Tenofovir disoproxil (CAS 1280130-08-6) is a chemical compound with molecular formula C19H30N5O10P and molecular weight 519.17303 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[[(2S)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate
Also Known As: Tenofovir disoproxil, Tenofovir S-Enantiomer, Tenofovir Impurity H, (S)-Tenofovir disoproxil, Tenofovir Impurity 233
Technical Specifications
| Molecular Formula | C19H30N5O10P |
| Molecular Weight | 519.17303 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 185.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 14 |
| Rotatable Bonds | 17 |
| Exact Mass | 519.17303 Da |
| Heavy Atoms | 35 |
| Complexity | 698.0 |
| SMILES | C[C@@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C |
| InChIKey | JFVZFKDSXNQEJW-AWEZNQCLSA-N |
Chemical Property Profile of Tenofovir disoproxil
Property Insights of Tenofovir disoproxil
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Tenofovir disoproxil. The TPSA of 185.0 Ų indicates high polarity, suggesting Tenofovir disoproxil may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Tenofovir disoproxil has 1 hydrogen bond donor(s) and 14 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Tenofovir disoproxil?
The CAS number of Tenofovir disoproxil is 1280130-08-6.
What is the molecular formula of Tenofovir disoproxil?
The molecular formula of Tenofovir disoproxil is C19H30N5O10P.
What is the molecular weight of Tenofovir disoproxil?
The molecular weight of Tenofovir disoproxil is 519.17303 g/mol.
Where can I buy Tenofovir disoproxil?
You can request a quote for Tenofovir disoproxil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Tenofovir disoproxil?
Yes, CoreyChem provides custom synthesis services for Tenofovir disoproxil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.