2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
TL;DR: 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone (CAS 1282143-20-7) is a chemical compound with molecular formula C19H23N5O and molecular weight 337.19025 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Also Known As: 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone, 2-(3,4-dihydroisoquinolin-2(1H)-yl)-1-(4-(pyrimidin-2-yl)piperazin-1-yl)ethanone, 2-(3,4-dihydroisoquinolin-2(1H)-yl)-1-[4-(pyrimidin-2-yl)piperazin-1-yl]ethanone
Technical Specifications
| Molecular Formula | C19H23N5O |
| Molecular Weight | 337.19025 g/mol |
| XLogP | 1.5 |
| Topological Polar Surface Area (TPSA) | 52.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 337.19025 Da |
| Heavy Atoms | 25 |
| Complexity | 445.0 |
| SMILES | C1CN(CC2=CC=CC=C21)CC(=O)N3CCN(CC3)C4=NC=CC=N4 |
| InChIKey | UBYYRCJNWUPOEA-UHFFFAOYSA-N |
Chemical Property Profile of 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
Property Insights of 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone
The XLogP value of 1.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone. With a topological polar surface area (TPSA) of 52.6 Ų, 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone?
The CAS number of 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone is 1282143-20-7.
What is the molecular formula of 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone?
The molecular formula of 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone is C19H23N5O.
What is the molecular weight of 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone?
The molecular weight of 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone is 337.19025 g/mol.
Where can I buy 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone?
You can request a quote for 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone?
Yes, CoreyChem provides custom synthesis services for 2-(3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-pyrimidin-2-ylpiperazin-1-yl)ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.