Bizelesin
TL;DR: Bizelesin (CAS 129655-21-6) is a chemical compound with molecular formula C43H36Cl2N8O5 and molecular weight 814.21857 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1,3-bis[2-[(8S)-8-(chloromethyl)-4-hydroxy-1-methyl-7,8-dihydro-3H-pyrrolo[3,2-e]indole-6-carbonyl]-1H-indol-5-yl]urea
Also Known As: BIZELESIN, Bizelesina, Bizelesine, bizelesinum, Bizelesin [USAN:INN]
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C43H36Cl2N8O5 |
| Molecular Weight | 814.21857 g/mol |
| XLogP | 6.5 |
| Topological Polar Surface Area (TPSA) | 185.0 Ų |
| Hydrogen Bond Donors | 8 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 814.21857 Da |
| Heavy Atoms | 58 |
| Complexity | 1470.0 |
| SMILES | CC1=CNC2=C(C=C3C(=C12)[C@@H](CN3C(=O)C4=CC5=C(N4)C=CC(=C5)NC(=O)NC6=CC7=C(C=C6)NC(=C7)C(=O)N8C[C@H](C9=C1C(=CNC1=C(C=C98)O)C)CCl)CCl)O |
| InChIKey | FONKWHRXTPJODV-DNQXCXABSA-N |
Chemical Property Profile of Bizelesin
Property Insights of Bizelesin
The XLogP value of 6.5 indicates that Bizelesin is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 185.0 Ų indicates high polarity, suggesting Bizelesin may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Bizelesin has 8 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Bizelesin?
The CAS number of Bizelesin is 129655-21-6.
What is the molecular formula of Bizelesin?
The molecular formula of Bizelesin is C43H36Cl2N8O5.
What is the molecular weight of Bizelesin?
The molecular weight of Bizelesin is 814.21857 g/mol.
Where can I buy Bizelesin?
You can request a quote for Bizelesin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Bizelesin?
Yes, CoreyChem provides custom synthesis services for Bizelesin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.