6-(4-Methylphenyl)pyridin-2(1H)-one
TL;DR: 6-(4-Methylphenyl)pyridin-2(1H)-one (CAS 129720-57-6) is a chemical compound with molecular formula C12H11NO and molecular weight 185.08406 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-(4-methylphenyl)-1H-pyridin-2-one
Also Known As: 6-(p-Tolyl)pyridin-2-ol, 2-HYDROXY-6-(4-METHYLPHENYL)PYRIDINE, 6-(4-methylphenyl)-1H-pyridin-2-one, 6-(4-tolyl)-2(1h)-pyridone, 6-(p-tolyl)-1H-pyridin-2-one
Technical Specifications
| Molecular Formula | C12H11NO |
| Molecular Weight | 185.08406 g/mol |
| XLogP | 2.2 |
| Topological Polar Surface Area (TPSA) | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 1 |
| Exact Mass | 185.08406 Da |
| Heavy Atoms | 14 |
| Complexity | 283.0 |
| SMILES | CC1=CC=C(C=C1)C2=CC=CC(=O)N2 |
| InChIKey | VKNQQUHTPUVQJD-UHFFFAOYSA-N |
Chemical Property Profile of 6-(4-Methylphenyl)pyridin-2(1H)-one
Property Insights of 6-(4-Methylphenyl)pyridin-2(1H)-one
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 6-(4-Methylphenyl)pyridin-2(1H)-one. With a topological polar surface area (TPSA) of 29.1 Ų, 6-(4-Methylphenyl)pyridin-2(1H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(4-Methylphenyl)pyridin-2(1H)-one has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 6-(4-Methylphenyl)pyridin-2(1H)-one?
The CAS number of 6-(4-Methylphenyl)pyridin-2(1H)-one is 129720-57-6.
What is the molecular formula of 6-(4-Methylphenyl)pyridin-2(1H)-one?
The molecular formula of 6-(4-Methylphenyl)pyridin-2(1H)-one is C12H11NO.
What is the molecular weight of 6-(4-Methylphenyl)pyridin-2(1H)-one?
The molecular weight of 6-(4-Methylphenyl)pyridin-2(1H)-one is 185.08406 g/mol.
Where can I buy 6-(4-Methylphenyl)pyridin-2(1H)-one?
You can request a quote for 6-(4-Methylphenyl)pyridin-2(1H)-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 6-(4-Methylphenyl)pyridin-2(1H)-one?
Yes, CoreyChem provides custom synthesis services for 6-(4-Methylphenyl)pyridin-2(1H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.