Aripiprazole
TL;DR: Aripiprazole (CAS 129722-12-9) is a chemical compound with molecular formula C23H27Cl2N3O2 and molecular weight 447.14804 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Also Known As: Aripiprazole, Abilify, Abilitat, aripiprazol, Discmelt
Application Areas
Top 5 of 13 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C23H27Cl2N3O2 |
| Molecular Weight | 447.14804 g/mol |
| XLogP | 4.6 |
| Topological Polar Surface Area (TPSA) | 44.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 7 |
| Exact Mass | 447.14804 Da |
| Heavy Atoms | 30 |
| Complexity | 559.0 |
| Melting Point | 137-140 |
| Boiling Point | 139.0-139.5 °C |
| Solubility | 0.00001% |
| SMILES | C1CC(=O)NC2=C1C=CC(=C2)OCCCCN3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl |
| InChIKey | CEUORZQYGODEFX-UHFFFAOYSA-N |
Chemical Property Profile of Aripiprazole
Property Insights of Aripiprazole
The XLogP value of 4.6 indicates that Aripiprazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 44.8 Ų, Aripiprazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Aripiprazole has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Aripiprazole?
The CAS number of Aripiprazole is 129722-12-9.
What is the molecular formula of Aripiprazole?
The molecular formula of Aripiprazole is C23H27Cl2N3O2.
What is the molecular weight of Aripiprazole?
The molecular weight of Aripiprazole is 447.14804 g/mol.
Where can I buy Aripiprazole?
You can request a quote for Aripiprazole directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Aripiprazole?
Yes, CoreyChem provides custom synthesis services for Aripiprazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.