5-Chloro-8-hydroxyquinoline
TL;DR: 5-Chloro-8-hydroxyquinoline (CAS 130-16-5) is a chemical compound with molecular formula C9H6ClNO and molecular weight 179.0138 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-chloroquinolin-8-ol
Also Known As: cloxyquin, Cloxiquine, 5-Chloroquinolin-8-ol, 5-CHLORO-8-HYDROXYQUINOLINE, 5-Chloro-8-quinolinol
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H6ClNO |
| Molecular Weight | 179.0138 g/mol |
| XLogP | 2.9 |
| Topological Polar Surface Area (TPSA) | 33.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 179.0138 Da |
| Heavy Atoms | 12 |
| Complexity | 165.0 |
| SMILES | C1=CC2=C(C=CC(=C2N=C1)O)Cl |
| InChIKey | CTQMJYWDVABFRZ-UHFFFAOYSA-N |
Product Description
Applications: 5-Chloro-8-hydroxyquinoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 5-Chloro-8-hydroxyquinoline (CAS 130-16-5) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, 5-Chloro-8-hydroxyquinoline (CAS 130-16-5) has the molecular formula C9H6ClNO and a molecular weight of 179.01 g/mol. It is also known as cloxyquin and Cloxiquine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 5-Chloro-8-hydroxyquinoline
Property Insights of 5-Chloro-8-hydroxyquinoline
The XLogP value of 2.9 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Chloro-8-hydroxyquinoline. With a topological polar surface area (TPSA) of 33.1 Ų, 5-Chloro-8-hydroxyquinoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Chloro-8-hydroxyquinoline has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Chloro-8-hydroxyquinoline?
The CAS number of 5-Chloro-8-hydroxyquinoline is 130-16-5.
What is the molecular formula of 5-Chloro-8-hydroxyquinoline?
The molecular formula of 5-Chloro-8-hydroxyquinoline is C9H6ClNO.
What is the molecular weight of 5-Chloro-8-hydroxyquinoline?
The molecular weight of 5-Chloro-8-hydroxyquinoline is 179.0138 g/mol.
What are the applications of 5-Chloro-8-hydroxyquinoline?
5-Chloro-8-hydroxyquinoline is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 5-Chloro-8-hydroxyquinoline...
Where can I buy 5-Chloro-8-hydroxyquinoline?
You can request a quote for 5-Chloro-8-hydroxyquinoline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Chloro-8-hydroxyquinoline?
Yes, CoreyChem provides custom synthesis services for 5-Chloro-8-hydroxyquinoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.