Levocetirizine Dihydrochloride
TL;DR: Levocetirizine Dihydrochloride (CAS 130018-77-8) is a chemical compound with molecular formula C21H27Cl3N2O3 and molecular weight 460.10873 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-[2-[4-[(R)-(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid;dihydrochloride
Also Known As: Levocetirizine dihydrochloride, Xyzal, Xusal, Levocetirizine 2HCl, Levocetirizine HCl
Technical Specifications
| Molecular Formula | C21H27Cl3N2O3 |
| Molecular Weight | 460.10873 g/mol |
| XLogP | 3.9918 |
| Topological Polar Surface Area (TPSA) | 53.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 8 |
| Exact Mass | 460.10873 Da |
| Heavy Atoms | 29 |
| Complexity | 443.0 |
| SMILES | C1CN(CCN1CCOCC(=O)O)[C@H](C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl |
| InChIKey | PGLIUCLTXOYQMV-GHVWMZMZSA-N |
Chemical Property Profile of Levocetirizine Dihydrochloride
Property Insights of Levocetirizine Dihydrochloride
The XLogP value of 3.9918 indicates that Levocetirizine Dihydrochloride is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.0 Ų, Levocetirizine Dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Levocetirizine Dihydrochloride has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Levocetirizine Dihydrochloride?
The CAS number of Levocetirizine Dihydrochloride is 130018-77-8.
What is the molecular formula of Levocetirizine Dihydrochloride?
The molecular formula of Levocetirizine Dihydrochloride is C21H27Cl3N2O3.
What is the molecular weight of Levocetirizine Dihydrochloride?
The molecular weight of Levocetirizine Dihydrochloride is 460.10873 g/mol.
Where can I buy Levocetirizine Dihydrochloride?
You can request a quote for Levocetirizine Dihydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Levocetirizine Dihydrochloride?
Yes, CoreyChem provides custom synthesis services for Levocetirizine Dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.