2-Hydroxytacrine
TL;DR: 2-Hydroxytacrine (CAS 1300730-81-7) is a chemical compound with molecular formula C13H14N2O and molecular weight 214.11061 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
9-amino-1,2,3,4-tetrahydroacridin-2-ol
Also Known As: 2-hydroxytacrine, 2-hydroxy-tacrine, 9-amino-1,2,3,4-tetrahydroacridin-2-ol, 2-OH-THA, 2-Acridinol,9-amino-1,2,3,4-tetrahydro-
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C13H14N2O |
| Molecular Weight | 214.11061 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 59.1 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 214.11061 Da |
| Heavy Atoms | 16 |
| Complexity | 258.0 |
| SMILES | C1CC2=NC3=CC=CC=C3C(=C2CC1O)N |
| InChIKey | PYCYYSWVRAEADT-UHFFFAOYSA-N |
Chemical Property Profile of 2-Hydroxytacrine
Property Insights of 2-Hydroxytacrine
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-Hydroxytacrine. With a topological polar surface area (TPSA) of 59.1 Ų, 2-Hydroxytacrine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-Hydroxytacrine has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2-Hydroxytacrine?
The CAS number of 2-Hydroxytacrine is 1300730-81-7.
What is the molecular formula of 2-Hydroxytacrine?
The molecular formula of 2-Hydroxytacrine is C13H14N2O.
What is the molecular weight of 2-Hydroxytacrine?
The molecular weight of 2-Hydroxytacrine is 214.11061 g/mol.
Where can I buy 2-Hydroxytacrine?
You can request a quote for 2-Hydroxytacrine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2-Hydroxytacrine?
Yes, CoreyChem provides custom synthesis services for 2-Hydroxytacrine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.