1-(p-Tolyl)piperazine dihydrochloride
TL;DR: 1-(p-Tolyl)piperazine dihydrochloride (CAS 13078-14-3) is a chemical compound with molecular formula C11H18Cl2N2 and molecular weight 248.0847 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(4-methylphenyl)piperazine;dihydrochloride
Also Known As: 1-(p-Tolyl)piperazine dihydrochloride, 1-(p-Tolyl)piperazine HCl, 1-(4-methylphenyl)piperazine dihydrochloride, 1-(4-Tolyl)piperazine 2HCl, 1-(4-methylphenyl)piperazine;dihydrochloride
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C11H18Cl2N2 |
| Molecular Weight | 248.0847 g/mol |
| XLogP | 2.25 |
| Topological Polar Surface Area (TPSA) | 15.3 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 248.0847 Da |
| Heavy Atoms | 15 |
| Complexity | 144.0 |
| SMILES | CC1=CC=C(C=C1)N2CCNCC2.Cl.Cl |
| InChIKey | PMGFOTNCJZITIM-UHFFFAOYSA-N |
Chemical Property Profile of 1-(p-Tolyl)piperazine dihydrochloride
Property Insights of 1-(p-Tolyl)piperazine dihydrochloride
The XLogP value of 2.25 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(p-Tolyl)piperazine dihydrochloride. With a topological polar surface area (TPSA) of 15.3 Ų, 1-(p-Tolyl)piperazine dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(p-Tolyl)piperazine dihydrochloride has 3 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(p-Tolyl)piperazine dihydrochloride?
The CAS number of 1-(p-Tolyl)piperazine dihydrochloride is 13078-14-3.
What is the molecular formula of 1-(p-Tolyl)piperazine dihydrochloride?
The molecular formula of 1-(p-Tolyl)piperazine dihydrochloride is C11H18Cl2N2.
What is the molecular weight of 1-(p-Tolyl)piperazine dihydrochloride?
The molecular weight of 1-(p-Tolyl)piperazine dihydrochloride is 248.0847 g/mol.
Where can I buy 1-(p-Tolyl)piperazine dihydrochloride?
You can request a quote for 1-(p-Tolyl)piperazine dihydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(p-Tolyl)piperazine dihydrochloride?
Yes, CoreyChem provides custom synthesis services for 1-(p-Tolyl)piperazine dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.