melphalan-N-4-hydroxyphenoxyacetamide
TL;DR: melphalan-N-4-hydroxyphenoxyacetamide (CAS 131089-09-3) is a chemical compound with molecular formula C21H24Cl2N2O5 and molecular weight 454.10623 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-3-[4-[bis(2-chloroethyl)amino]phenyl]-2-[[2-(4-hydroxyphenoxy)acetyl]amino]propanoic acid
Also Known As: MelPO, Melphalan-N-4-hydroxyphenoxyacetamide, 4-(Bis(2-chloroethyl)amino)-N-((4-hydroxyphenoxy)acetyl)-L-phenylalanine, (2S)-3-[4-[bis(2-chloroethyl)amino]phenyl]-2-[[2-(4-hydroxyphenoxy)acetyl]amino]propanoic acid, 4-[Bis(2-chloroethyl)amino]-N-[(4-hydroxyphenoxy)acetyl]-L-phenylalanine
Technical Specifications
| Molecular Formula | C21H24Cl2N2O5 |
| Molecular Weight | 454.10623 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 99.1 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 12 |
| Exact Mass | 454.10623 Da |
| Heavy Atoms | 30 |
| Complexity | 518.0 |
| SMILES | C1=CC(=CC=C1C[C@@H](C(=O)O)NC(=O)COC2=CC=C(C=C2)O)N(CCCl)CCCl |
| InChIKey | ZVHIURZYHWNOKI-IBGZPJMESA-N |
Chemical Property Profile of melphalan-N-4-hydroxyphenoxyacetamide
Property Insights of melphalan-N-4-hydroxyphenoxyacetamide
The XLogP value of 3.8 indicates that melphalan-N-4-hydroxyphenoxyacetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 99.1 Ų falls within the moderate polarity range, balancing permeability and solubility for melphalan-N-4-hydroxyphenoxyacetamide. Following Lipinski's Rule of Five, melphalan-N-4-hydroxyphenoxyacetamide has 3 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of melphalan-N-4-hydroxyphenoxyacetamide?
The CAS number of melphalan-N-4-hydroxyphenoxyacetamide is 131089-09-3.
What is the molecular formula of melphalan-N-4-hydroxyphenoxyacetamide?
The molecular formula of melphalan-N-4-hydroxyphenoxyacetamide is C21H24Cl2N2O5.
What is the molecular weight of melphalan-N-4-hydroxyphenoxyacetamide?
The molecular weight of melphalan-N-4-hydroxyphenoxyacetamide is 454.10623 g/mol.
Where can I buy melphalan-N-4-hydroxyphenoxyacetamide?
You can request a quote for melphalan-N-4-hydroxyphenoxyacetamide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for melphalan-N-4-hydroxyphenoxyacetamide?
Yes, CoreyChem provides custom synthesis services for melphalan-N-4-hydroxyphenoxyacetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.