![1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine structure](/static/products/1311/131136-84-0.webp)
1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine
TL;DR: 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine (CAS 131136-84-0) is a chemical compound with molecular formula C16H14F6N4 and molecular weight 376.11227 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1,4-bis[5-(trifluoromethyl)-2-pyridinyl]piperazine
Also Known As: 1,4-bis[5-(trifluoromethyl)pyridin-2-yl]piperazine, 1,4-BIS(5-(TRIFLUOROMETHYL)-2-PYRIDYL)PIPERAZINE, 1,4-bis[5-(trifluoromethyl)-2-pyridyl]piperazine, 1,4-Bis(5-(trifluoromethyl)pyridin-2-yl)piperazine, AF-399/33192017
Technical Specifications
| Molecular Formula | C16H14F6N4 |
| Molecular Weight | 376.11227 g/mol |
| XLogP | 3.9 |
| Topological Polar Surface Area (TPSA) | 32.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 2 |
| Exact Mass | 376.11227 Da |
| Heavy Atoms | 26 |
| Complexity | 419.0 |
| SMILES | C1CN(CCN1C2=NC=C(C=C2)C(F)(F)F)C3=NC=C(C=C3)C(F)(F)F |
| InChIKey | NWJPVXBIUDRQLH-UHFFFAOYSA-N |
Chemical Property Profile of 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine
Property Insights of 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine
The XLogP value of 3.9 indicates that 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 32.3 Ų, 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine has 0 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine?
The CAS number of 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine is 131136-84-0.
What is the molecular formula of 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine?
The molecular formula of 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine is C16H14F6N4.
What is the molecular weight of 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine?
The molecular weight of 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine is 376.11227 g/mol.
Where can I buy 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine?
You can request a quote for 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine?
Yes, CoreyChem provides custom synthesis services for 1,4-Bis[5-(trifluoromethyl)pyridin-2-yl]piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.