trans-4-Fluoro-D-proline
TL;DR: trans-4-Fluoro-D-proline (CAS 131176-02-8) is a chemical compound with molecular formula C5H8FNO2 and molecular weight 133.05391 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2R,4S)-4-fluoropyrrolidin-1-ium-2-carboxylate
Also Known As: trans-4-Fluoro-D-proline, (2R,4S)-4-fluoropyrrolidin-1-ium-2-carboxylate
Technical Specifications
| Molecular Formula | C5H8FNO2 |
| Molecular Weight | 133.05391 g/mol |
| XLogP | -1.7 |
| Topological Polar Surface Area (TPSA) | 56.7 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 0 |
| Exact Mass | 133.05391 Da |
| Heavy Atoms | 9 |
| Complexity | 123.0 |
| SMILES | C1[C@@H](C[NH2+][C@H]1C(=O)[O-])F |
| InChIKey | ZIWHMENIDGOELV-IUYQGCFVSA-N |
Chemical Property Profile of trans-4-Fluoro-D-proline
Property Insights of trans-4-Fluoro-D-proline
The XLogP value of -1.7 indicates that trans-4-Fluoro-D-proline is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 56.7 Ų, trans-4-Fluoro-D-proline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, trans-4-Fluoro-D-proline has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of trans-4-Fluoro-D-proline?
The CAS number of trans-4-Fluoro-D-proline is 131176-02-8.
What is the molecular formula of trans-4-Fluoro-D-proline?
The molecular formula of trans-4-Fluoro-D-proline is C5H8FNO2.
What is the molecular weight of trans-4-Fluoro-D-proline?
The molecular weight of trans-4-Fluoro-D-proline is 133.05391 g/mol.
Where can I buy trans-4-Fluoro-D-proline?
You can request a quote for trans-4-Fluoro-D-proline directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for trans-4-Fluoro-D-proline?
Yes, CoreyChem provides custom synthesis services for trans-4-Fluoro-D-proline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.