Trimetazidine Dihydrochloride
TL;DR: Trimetazidine Dihydrochloride (CAS 13171-25-0) is a chemical compound with molecular formula C14H24Cl2N2O3 and molecular weight 338.1164 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;dihydrochloride
Also Known As: Trimetazidine dihydrochloride, Kyurinett, Trimetazidine HCl, Trimetazidine hydrochloride, Trimetajust
Application Areas
Top 5 of 4 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H24Cl2N2O3 |
| Molecular Weight | 338.1164 g/mol |
| XLogP | 1.96 |
| Topological Polar Surface Area (TPSA) | 43.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 5 |
| Exact Mass | 338.1164 Da |
| Heavy Atoms | 21 |
| Complexity | 259.0 |
| SMILES | COC1=C(C(=C(C=C1)CN2CCNCC2)OC)OC.Cl.Cl |
| InChIKey | VYFLPFGUVGMBEP-UHFFFAOYSA-N |
Chemical Property Profile of Trimetazidine Dihydrochloride
Property Insights of Trimetazidine Dihydrochloride
The XLogP value of 1.96 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trimetazidine Dihydrochloride. With a topological polar surface area (TPSA) of 43.0 Ų, Trimetazidine Dihydrochloride exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Trimetazidine Dihydrochloride has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trimetazidine Dihydrochloride?
The CAS number of Trimetazidine Dihydrochloride is 13171-25-0.
What is the molecular formula of Trimetazidine Dihydrochloride?
The molecular formula of Trimetazidine Dihydrochloride is C14H24Cl2N2O3.
What is the molecular weight of Trimetazidine Dihydrochloride?
The molecular weight of Trimetazidine Dihydrochloride is 338.1164 g/mol.
Where can I buy Trimetazidine Dihydrochloride?
You can request a quote for Trimetazidine Dihydrochloride directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trimetazidine Dihydrochloride?
Yes, CoreyChem provides custom synthesis services for Trimetazidine Dihydrochloride and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.