Naproxen
TL;DR: Naproxen (CAS 131991-52-1) is a chemical compound with molecular formula C14H14O3 and molecular weight 230.0943 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
Also Known As: NAPROXEN, (S)-Naproxen, Naprosyn, Equiproxen, Naproxene
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C14H14O3 |
| Molecular Weight | 230.0943 g/mol |
| XLogP | 3.3 |
| Topological Polar Surface Area (TPSA) | 46.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 230.0943 Da |
| Heavy Atoms | 17 |
| Complexity | 277.0 |
| Melting Point | 152°C |
| Solubility | 15.9 |
| SMILES | C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)O |
| InChIKey | CMWTZPSULFXXJA-VIFPVBQESA-N |
Chemical Property Profile of Naproxen
Property Insights of Naproxen
The XLogP value of 3.3 indicates that Naproxen is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 46.5 Ų, Naproxen exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Naproxen has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Naproxen?
The CAS number of Naproxen is 131991-52-1.
What is the molecular formula of Naproxen?
The molecular formula of Naproxen is C14H14O3.
What is the molecular weight of Naproxen?
The molecular weight of Naproxen is 230.0943 g/mol.
Where can I buy Naproxen?
You can request a quote for Naproxen directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Naproxen?
Yes, CoreyChem provides custom synthesis services for Naproxen and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.