(+-)-Chlorpheniramine
TL;DR: (+-)-Chlorpheniramine (CAS 132-22-9) is a chemical compound with molecular formula C16H19ClN2 and molecular weight 274.1237 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
Also Known As: chlorpheniramine, Chlorphenamine, Haynon, Clorfeniramina, Clorfenamina
Application Areas
Top 5 of 20 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C16H19ClN2 |
| Molecular Weight | 274.1237 g/mol |
| XLogP | 3.4 |
| Topological Polar Surface Area (TPSA) | 16.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 5 |
| Exact Mass | 274.1237 Da |
| Heavy Atoms | 19 |
| Complexity | 249.0 |
| Melting Point | 130 - 135 °C |
| Boiling Point | 142 |
| Refractive Index | BOX LIKE PRISMS & IRREGULAR FRAGMENTS; INDEX OF REFRACTION: 1.533 (ALPHA); 1.668 (BETA; INTERMEDIATE INDEX); LESS THAN 1.734 (GAMMA; INCLINED) /MALEATE/ |
| Solubility | 5500 |
| SMILES | CN(C)CCC(C1=CC=C(C=C1)Cl)C2=CC=CC=N2 |
| InChIKey | SOYKEARSMXGVTM-UHFFFAOYSA-N |
Product Description
Applications: (+-)-Chlorpheniramine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies (+-)-Chlorpheniramine (CAS 132-22-9) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
(+-)-Chlorpheniramine is a pharmaceutical intermediate identified by CAS number 132-22-9 and the molecular formula C16H19ClN2 and a molecular weight of 274.12 g/mol. Physically, the compound has a solubility: 5500. It is also known as chlorpheniramine and Chlorphenamine.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of (+-)-Chlorpheniramine
Property Insights of (+-)-Chlorpheniramine
The XLogP value of 3.4 indicates that (+-)-Chlorpheniramine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 16.1 Ų, (+-)-Chlorpheniramine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (+-)-Chlorpheniramine has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of (+-)-Chlorpheniramine?
The CAS number of (+-)-Chlorpheniramine is 132-22-9.
What is the molecular formula of (+-)-Chlorpheniramine?
The molecular formula of (+-)-Chlorpheniramine is C16H19ClN2.
What is the molecular weight of (+-)-Chlorpheniramine?
The molecular weight of (+-)-Chlorpheniramine is 274.1237 g/mol.
What are the applications of (+-)-Chlorpheniramine?
(+-)-Chlorpheniramine is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies (+-)-Chlorpheniramine (CAS...
Where can I buy (+-)-Chlorpheniramine?
You can request a quote for (+-)-Chlorpheniramine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for (+-)-Chlorpheniramine?
Yes, CoreyChem provides custom synthesis services for (+-)-Chlorpheniramine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.