4-Hydroxyphenylnaftodipil
TL;DR: 4-Hydroxyphenylnaftodipil (CAS 132194-31-1) is a chemical compound with molecular formula C24H28N2O4 and molecular weight 408.2049 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-[4-(2-hydroxy-3-naphthalen-1-yloxypropyl)piperazin-1-yl]-3-methoxyphenol
Also Known As: (Phenyl)hydroxynaftopidil, 4-Hydroxyphenylnaftodipil, 4-[4-(2-hydroxy-3-naphthalen-1-yloxypropyl)piperazin-1-yl]-3-methoxyphenol, 1-(2-Methoxy-4-hydroxyphenyl)-4-[3-(naphth-1-yloxy)-2-hydroxypropyl]-piperazine, 1-[4-(2-Methoxy-4-hydroxyphenyl)-1-piperazinyl]-3-(1-naphthyloxy)-2-propanol
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C24H28N2O4 |
| Molecular Weight | 408.2049 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 65.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 408.2049 Da |
| Heavy Atoms | 30 |
| Complexity | 513.0 |
| SMILES | COC1=C(C=CC(=C1)O)N2CCN(CC2)CC(COC3=CC=CC4=CC=CC=C43)O |
| InChIKey | AMXMCPNWQJKZCZ-UHFFFAOYSA-N |
Chemical Property Profile of 4-Hydroxyphenylnaftodipil
Property Insights of 4-Hydroxyphenylnaftodipil
The XLogP value of 3.8 indicates that 4-Hydroxyphenylnaftodipil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 4-Hydroxyphenylnaftodipil. Following Lipinski's Rule of Five, 4-Hydroxyphenylnaftodipil has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Hydroxyphenylnaftodipil?
The CAS number of 4-Hydroxyphenylnaftodipil is 132194-31-1.
What is the molecular formula of 4-Hydroxyphenylnaftodipil?
The molecular formula of 4-Hydroxyphenylnaftodipil is C24H28N2O4.
What is the molecular weight of 4-Hydroxyphenylnaftodipil?
The molecular weight of 4-Hydroxyphenylnaftodipil is 408.2049 g/mol.
Where can I buy 4-Hydroxyphenylnaftodipil?
You can request a quote for 4-Hydroxyphenylnaftodipil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Hydroxyphenylnaftodipil?
Yes, CoreyChem provides custom synthesis services for 4-Hydroxyphenylnaftodipil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.