TL;DR: (Z)-2-((E)-(4-ethoxybenzylidene)hydrazono)-4-(4-methoxyphenyl)-2,3-dihydrothiazole (CAS 1322212-54-3) is a chemical compound with molecular formula C19H19N3O2S and molecular weight 353.1198 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[(E)-(4-ethoxyphenyl)methylideneamino]-4-(4-methoxyphenyl)-1,3-thiazol-2-amine
Also Known As: (Z)-2-((E)-(4-ethoxybenzylidene)hydrazono)-4-(4-methoxyphenyl)-2,3-dihydrothiazole, F0486-2254, (2Z)-2-[(E)-2-[(4-ethoxyphenyl)methylidene]hydrazin-1-ylidene]-4-(4-methoxyphenyl)-2,3-dihydro-1,3-thiazole, (E)-2-(2-(4-ethoxybenzylidene)hydrazinyl)-4-(4-methoxyphenyl)thiazole, [(1E)-2-(4-ethoxyphenyl)-1-azavinyl][4-(4-methoxyphenyl)(1,3-thiazol-2-yl)]ami ne
| Molecular Formula | C19H19N3O2S |
| Molecular Weight | 353.1198 g/mol |
| XLogP | 4.9 |
| Topological Polar Surface Area (TPSA) | 84.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 353.1198 Da |
| Heavy Atoms | 25 |
| Complexity | 407.0 |
| SMILES | CCOC1=CC=C(C=C1)/C=N/NC2=NC(=CS2)C3=CC=C(C=C3)OC |
| InChIKey | TYQNCINRWWCHPT-UDWIEESQSA-N |
The XLogP value of 4.9 indicates that (Z)-2-((E)-(4-ethoxybenzylidene)hydrazono)-4-(4-methoxyphenyl)-2,3-dihydrothiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 84.0 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-2-((E)-(4-ethoxybenzylidene)hydrazono)-4-(4-methoxyphenyl)-2,3-dihydrothiazole. Following Lipinski's Rule of Five, (Z)-2-((E)-(4-ethoxybenzylidene)hydrazono)-4-(4-methoxyphenyl)-2,3-dihydrothiazole has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of (Z)-2-((E)-(4-ethoxybenzylidene)hydrazono)-4-(4-methoxyphenyl)-2,3-dihydrothiazole is 1322212-54-3.
The molecular formula of (Z)-2-((E)-(4-ethoxybenzylidene)hydrazono)-4-(4-methoxyphenyl)-2,3-dihydrothiazole is C19H19N3O2S.
The molecular weight of (Z)-2-((E)-(4-ethoxybenzylidene)hydrazono)-4-(4-methoxyphenyl)-2,3-dihydrothiazole is 353.1198 g/mol.
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