Zifrosilone
TL;DR: Zifrosilone (CAS 132236-18-1) is a chemical compound with molecular formula C11H13F3OSi and molecular weight 246.06877 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2,2,2-trifluoro-1-(3-trimethylsilylphenyl)ethanone
Also Known As: ZIFROSILONE, zifrosilona, zifrosilonum, Zifrosilone [USAN:INN], Zifrosilone (USAN)
Application Areas
Top 5 of 7 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C11H13F3OSi |
| Molecular Weight | 246.06877 g/mol |
| XLogP | 2.98 |
| Topological Polar Surface Area (TPSA) | 17.1 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 246.06877 Da |
| Heavy Atoms | 16 |
| Complexity | 267.0 |
| SMILES | C[Si](C)(C)C1=CC=CC(=C1)C(=O)C(F)(F)F |
| InChIKey | GAPOASFZXBWUGS-UHFFFAOYSA-N |
Chemical Property Profile of Zifrosilone
Property Insights of Zifrosilone
The XLogP value of 2.98 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Zifrosilone. With a topological polar surface area (TPSA) of 17.1 Ų, Zifrosilone exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Zifrosilone has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Zifrosilone?
The CAS number of Zifrosilone is 132236-18-1.
What is the molecular formula of Zifrosilone?
The molecular formula of Zifrosilone is C11H13F3OSi.
What is the molecular weight of Zifrosilone?
The molecular weight of Zifrosilone is 246.06877 g/mol.
Where can I buy Zifrosilone?
You can request a quote for Zifrosilone directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Zifrosilone?
Yes, CoreyChem provides custom synthesis services for Zifrosilone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.