Aliskiren
TL;DR: Aliskiren (CAS 1327153-71-8) is a chemical compound with molecular formula C30H53N3O6 and molecular weight 551.39343 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide
Also Known As: Aliskiren, Rasilez, Tekturna, aliskirene, Aliskireno
Technical Specifications
| Molecular Formula | C30H53N3O6 |
| Molecular Weight | 551.39343 g/mol |
| XLogP | 3.5 |
| Topological Polar Surface Area (TPSA) | 146.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 19 |
| Exact Mass | 551.39343 Da |
| Heavy Atoms | 39 |
| Complexity | 717.0 |
| SMILES | CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N |
| InChIKey | UXOWGYHJODZGMF-QORCZRPOSA-N |
Chemical Property Profile of Aliskiren
Property Insights of Aliskiren
The XLogP value of 3.5 indicates that Aliskiren is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 146.0 Ų indicates high polarity, suggesting Aliskiren may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Aliskiren has 4 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of Aliskiren?
The CAS number of Aliskiren is 1327153-71-8.
What is the molecular formula of Aliskiren?
The molecular formula of Aliskiren is C30H53N3O6.
What is the molecular weight of Aliskiren?
The molecular weight of Aliskiren is 551.39343 g/mol.
Where can I buy Aliskiren?
You can request a quote for Aliskiren directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Aliskiren?
Yes, CoreyChem provides custom synthesis services for Aliskiren and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.