5-Dehydrofumagillol
TL;DR: 5-Dehydrofumagillol (CAS 132746-88-4) is a chemical compound with molecular formula C16H24O4 and molecular weight 280.16745 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(3R,4S,5S)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-one
Also Known As: 6-Ketofumagillol, 5-dehydrofumagillol, 6-oxo-6-deoxyfumagillol, J2.021.215B, (3R)-4beta-[(2R,3R)-2-Methyl-3-[3-methyl-2-butenyl]oxiranyl]-5alpha-methoxy-1-oxaspiro[2.5]octane-6-one
Technical Specifications
| Molecular Formula | C16H24O4 |
| Molecular Weight | 280.16745 g/mol |
| XLogP | 1.7 |
| Topological Polar Surface Area (TPSA) | 51.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 280.16745 Da |
| Heavy Atoms | 20 |
| Complexity | 453.0 |
| SMILES | CC(=CC[C@@H]1[C@@](O1)(C)[C@H]2[C@@H](C(=O)CC[C@]23CO3)OC)C |
| InChIKey | RKYFKXLMWVUYJY-SUJAAXHWSA-N |
Chemical Property Profile of 5-Dehydrofumagillol
Property Insights of 5-Dehydrofumagillol
The XLogP value of 1.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Dehydrofumagillol. With a topological polar surface area (TPSA) of 51.4 Ų, 5-Dehydrofumagillol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Dehydrofumagillol has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Dehydrofumagillol?
The CAS number of 5-Dehydrofumagillol is 132746-88-4.
What is the molecular formula of 5-Dehydrofumagillol?
The molecular formula of 5-Dehydrofumagillol is C16H24O4.
What is the molecular weight of 5-Dehydrofumagillol?
The molecular weight of 5-Dehydrofumagillol is 280.16745 g/mol.
Where can I buy 5-Dehydrofumagillol?
You can request a quote for 5-Dehydrofumagillol directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Dehydrofumagillol?
Yes, CoreyChem provides custom synthesis services for 5-Dehydrofumagillol and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.