TL;DR: Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl- (CAS 132776-21-7) is a chemical compound with molecular formula C10H12F2N2O4 and molecular weight 262.0765 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(2R,3S,4R,5R)-3,4-difluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: 2'-F-ribo-FLT, Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl-, 3'-Deoxy-2',3'-difluorothymidine, 1-(2,3-Dideoxy-2,3-difluoro-beta-D-ribofuranosyl)thymine, 2',3'-Dideoxy-2',3'-difluoro-5-methyluridine
| Molecular Formula | C10H12F2N2O4 |
| Molecular Weight | 262.0765 g/mol |
| XLogP | -0.4 |
| Topological Polar Surface Area (TPSA) | 78.9 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 2 |
| Exact Mass | 262.0765 Da |
| Heavy Atoms | 18 |
| Complexity | 415.0 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)F)F |
| InChIKey | WZJLGLRFQDVYET-JXOAFFINSA-N |
The XLogP value of -0.4 indicates that Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl- is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 78.9 Ų falls within the moderate polarity range, balancing permeability and solubility for Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl-. Following Lipinski's Rule of Five, Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl- has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl- is 132776-21-7.
The molecular formula of Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl- is C10H12F2N2O4.
The molecular weight of Uridine, 2',3'-dideoxy-2',3'-difluoro-5-methyl- is 262.0765 g/mol.
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