2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine
TL;DR: 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine (CAS 132778-81-5) is a chemical compound with molecular formula C10H12FN5O4 and molecular weight 285.08734 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(2R,3S,4S,5R)-3-azido-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Also Known As: AZdd-3'-F-methyl-U, Fluorinated Sugar Analog, 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine, 2'-Azido-3'-deoxy-3'-fluorothymidine, Uridine, 2'-azido-2',3'-dideoxy-3'-fluoro-5-methyl-
Technical Specifications
| Molecular Formula | C10H12FN5O4 |
| Molecular Weight | 285.08734 g/mol |
| XLogP | 0.3 |
| Topological Polar Surface Area (TPSA) | 93.2 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 285.08734 Da |
| Heavy Atoms | 20 |
| Complexity | 518.0 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)F)N=[N+]=[N-] |
| InChIKey | WPVHNRXKTMGASU-JXOAFFINSA-N |
Chemical Property Profile of 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine
Property Insights of 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine. The TPSA of 93.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine. Following Lipinski's Rule of Five, 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine?
The CAS number of 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine is 132778-81-5.
What is the molecular formula of 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine?
The molecular formula of 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine is C10H12FN5O4.
What is the molecular weight of 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine?
The molecular weight of 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine is 285.08734 g/mol.
Where can I buy 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine?
You can request a quote for 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine?
Yes, CoreyChem provides custom synthesis services for 2'-Azido-2',3'-dideoxy-3'-fluoro-5-methyluridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.