Trichlormethiazide
TL;DR: Trichlormethiazide (CAS 133-67-5) is a chemical compound with molecular formula C8H8Cl3N3O4S2 and molecular weight 378.9022 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-chloro-3-(dichloromethyl)-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Also Known As: trichlormethiazide, Trichloromethiazide, Naqua, Metahydrin, Trichlormetazid
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H8Cl3N3O4S2 |
| Molecular Weight | 378.9022 g/mol |
| XLogP | 0.6 |
| Topological Polar Surface Area (TPSA) | 135.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.9022 Da |
| Heavy Atoms | 20 |
| Complexity | 571.0 |
| Melting Point | 270 |
| Solubility | 800 |
| SMILES | C1=C2C(=CC(=C1Cl)S(=O)(=O)N)S(=O)(=O)NC(N2)C(Cl)Cl |
| InChIKey | LMJSLTNSBFUCMU-UHFFFAOYSA-N |
Chemical Property Profile of Trichlormethiazide
Property Insights of Trichlormethiazide
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Trichlormethiazide. The TPSA of 135.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Trichlormethiazide. Following Lipinski's Rule of Five, Trichlormethiazide has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Trichlormethiazide?
The CAS number of Trichlormethiazide is 133-67-5.
What is the molecular formula of Trichlormethiazide?
The molecular formula of Trichlormethiazide is C8H8Cl3N3O4S2.
What is the molecular weight of Trichlormethiazide?
The molecular weight of Trichlormethiazide is 378.9022 g/mol.
Where can I buy Trichlormethiazide?
You can request a quote for Trichlormethiazide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Trichlormethiazide?
Yes, CoreyChem provides custom synthesis services for Trichlormethiazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.