1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil
TL;DR: 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil (CAS 133488-40-1) is a chemical compound with molecular formula C10H14FN3O5 and molecular weight 275.09174 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-[(2R,4S)-4-amino-5-[(1S)-1,2-dihydroxyethyl]oxolan-2-yl]-5-fluoropyrimidine-2,4-dione
Also Known As: 3NH-D-ribo-ddU deriv., 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil, 2,4(1H,3H)-Pyrimidinedione, 1-(3-amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluoro-, 1-(3-Amino-2,3-dideoxy-.beta.-D-ribo-hexofuranosyl)-5-fluorouracil, 1-(3-Amino-2,3-dideoxyhexofuranosyl)-5-fluoro-4-hydroxypyrimidin-2(1H)-one
Technical Specifications
| Molecular Formula | C10H14FN3O5 |
| Molecular Weight | 275.09174 g/mol |
| XLogP | -2.0 |
| Topological Polar Surface Area (TPSA) | 125.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 3 |
| Exact Mass | 275.09174 Da |
| Heavy Atoms | 19 |
| Complexity | 429.0 |
| SMILES | C1[C@@H](C(O[C@H]1N2C=C(C(=O)NC2=O)F)[C@H](CO)O)N |
| InChIKey | YUNLZAPEXNEVJA-QBARFFCXSA-N |
Chemical Property Profile of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil
Property Insights of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil
The XLogP value of -2.0 indicates that 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 125.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil. Following Lipinski's Rule of Five, 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil has 4 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil?
The CAS number of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil is 133488-40-1.
What is the molecular formula of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil?
The molecular formula of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil is C10H14FN3O5.
What is the molecular weight of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil?
The molecular weight of 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil is 275.09174 g/mol.
Where can I buy 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil?
You can request a quote for 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil?
Yes, CoreyChem provides custom synthesis services for 1-(3-Amino-2,3-dideoxy-beta-D-ribo-hexofuranosyl)-5-fluorouracil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.