12-Hydroxynevirapine
TL;DR: 12-Hydroxynevirapine (CAS 133627-24-4) is a chemical compound with molecular formula C15H14N4O2 and molecular weight 282.11166 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
2-cyclopropyl-7-(hydroxymethyl)-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one
Also Known As: 12-Hydroxynevirapine, 12-hydroxy-NVP, 12-Hydroxy nevirapine, 12-hydroxy-nevirapine, starbld0035142
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C15H14N4O2 |
| Molecular Weight | 282.11166 g/mol |
| XLogP | 0.7 |
| Topological Polar Surface Area (TPSA) | 78.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 282.11166 Da |
| Heavy Atoms | 21 |
| Complexity | 414.0 |
| SMILES | C1CC1N2C3=C(C=CC=N3)C(=O)NC4=C(C=CN=C42)CO |
| InChIKey | SEBABOMFNCVZGF-UHFFFAOYSA-N |
Chemical Property Profile of 12-Hydroxynevirapine
Property Insights of 12-Hydroxynevirapine
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 12-Hydroxynevirapine. The TPSA of 78.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 12-Hydroxynevirapine. Following Lipinski's Rule of Five, 12-Hydroxynevirapine has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 12-Hydroxynevirapine?
The CAS number of 12-Hydroxynevirapine is 133627-24-4.
What is the molecular formula of 12-Hydroxynevirapine?
The molecular formula of 12-Hydroxynevirapine is C15H14N4O2.
What is the molecular weight of 12-Hydroxynevirapine?
The molecular weight of 12-Hydroxynevirapine is 282.11166 g/mol.
Where can I buy 12-Hydroxynevirapine?
You can request a quote for 12-Hydroxynevirapine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 12-Hydroxynevirapine?
Yes, CoreyChem provides custom synthesis services for 12-Hydroxynevirapine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.