1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one
TL;DR: 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one (CAS 133747-71-4) is a chemical compound with molecular formula C11H12ClNO2 and molecular weight 225.05565 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-(2-chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one
Also Known As: 1-(2-chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one, 1-(2-chlorophenyl)-4-hydroxymethyl-2-pyrrolidone, 1-(2-Chlorophenyl)-4-(hydroxymethyl)-2-pyrrolidinone
Technical Specifications
| Molecular Formula | C11H12ClNO2 |
| Molecular Weight | 225.05565 g/mol |
| XLogP | 1.2 |
| Topological Polar Surface Area (TPSA) | 40.5 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 225.05565 Da |
| Heavy Atoms | 15 |
| Complexity | 247.0 |
| SMILES | C1C(CN(C1=O)C2=CC=CC=C2Cl)CO |
| InChIKey | AQJURVKZGWQWAH-UHFFFAOYSA-N |
Chemical Property Profile of 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one
Property Insights of 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one
The XLogP value of 1.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one. With a topological polar surface area (TPSA) of 40.5 Ų, 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one?
The CAS number of 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one is 133747-71-4.
What is the molecular formula of 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one?
The molecular formula of 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one is C11H12ClNO2.
What is the molecular weight of 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one?
The molecular weight of 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one is 225.05565 g/mol.
Where can I buy 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one?
You can request a quote for 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one?
Yes, CoreyChem provides custom synthesis services for 1-(2-Chlorophenyl)-4-(hydroxymethyl)pyrrolidin-2-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.