1-Naphthylamine
TL;DR: 1-Naphthylamine (CAS 134-32-7) is a chemical compound with molecular formula C10H9N and molecular weight 143.0735 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
naphthalen-1-amine
Also Known As: 1-NAPHTHYLAMINE, 1-Aminonaphthalene, naphthalen-1-amine, 1-Naphthalenamine, Naphthalidine
Application Areas
Top 5 of 22 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C10H9N |
| Molecular Weight | 143.0735 g/mol |
| XLogP | 2.2 |
| Topological Polar Surface Area (TPSA) | 26.0 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 143.0735 Da |
| Heavy Atoms | 11 |
| Complexity | 133.0 |
| Melting Point | 122 °F (NTP, 1992) |
| Boiling Point | 574 °F at 760 mmHg (NTP, 1992) |
| Density | 1.12 at 77 °F (USCG, 1999) - Denser than water; will sink |
| Flash Point | 315 °F (NTP, 1992) |
| Vapor Pressure | 1 mmHg at 219.7 °F ; 5 mmHg at 279.9 °F (NTP, 1992) |
| Refractive Index | INDEX OF REFRACTION: 1.67034 @ 51 °C/D; MAX ABSORPTION (DIL ALCOHOL): 242 NM (LOG E= 4.27); 320 NM (LOG E= 3.71) |
| Solubility | less than 1 mg/mL at 66 °F (NTP, 1992) |
| SMILES | C1=CC=C2C(=C1)C=CC=C2N |
| InChIKey | RUFPHBVGCFYCNW-UHFFFAOYSA-N |
Product Description
Applications: 1-Naphthylamine is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 1-Naphthylamine (CAS 134-32-7) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A heterocyclic building block supplied by CoreyChem, 1-Naphthylamine (CAS 134-32-7) has the molecular formula C10H9N and a molecular weight of 143.07 g/mol. Reported properties include a density of 1.12 at 77 °F (USCG, 1999) - Denser than water; will sink g/cm³, a solubility: less than 1 mg/mL at 66 °F (NTP, 1992). It is also known as 1-NAPHTHYLAMINE and 1-Aminonaphthalene.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 1-Naphthylamine
Property Insights of 1-Naphthylamine
The XLogP value of 2.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 1-Naphthylamine. With a topological polar surface area (TPSA) of 26.0 Ų, 1-Naphthylamine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-Naphthylamine has 1 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-Naphthylamine?
The CAS number of 1-Naphthylamine is 134-32-7.
What is the molecular formula of 1-Naphthylamine?
The molecular formula of 1-Naphthylamine is C10H9N.
What is the molecular weight of 1-Naphthylamine?
The molecular weight of 1-Naphthylamine is 143.0735 g/mol.
What are the applications of 1-Naphthylamine?
1-Naphthylamine is used in heterocycle construction in medicinal chemistry and agrochemical discovery, as well as pharmaceutical synthesis routes and API production. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies 1-Naphthylamine (CAS 134-32-7) with...
Where can I buy 1-Naphthylamine?
You can request a quote for 1-Naphthylamine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-Naphthylamine?
Yes, CoreyChem provides custom synthesis services for 1-Naphthylamine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.