5-Fluorodeoxyuridine monophosphate
TL;DR: 5-Fluorodeoxyuridine monophosphate (CAS 134-46-3) is a chemical compound with molecular formula C9H12FN2O8P and molecular weight 326.03152 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[(2R,3S,5R)-5-(5-fluoro-2,4-dioxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate
Also Known As: FdUMP, 5-Fluoro-dUMP, 5-fluorodeoxyuridine monophosphate, 5FdUMP, F-dUMP
Application Areas
Top 5 of 9 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H12FN2O8P |
| Molecular Weight | 326.03152 g/mol |
| XLogP | -2.8 |
| Topological Polar Surface Area (TPSA) | 146.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 9 |
| Rotatable Bonds | 4 |
| Exact Mass | 326.03152 Da |
| Heavy Atoms | 21 |
| Complexity | 534.0 |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)COP(=O)(O)O)O |
| InChIKey | HFEKDTCAMMOLQP-RRKCRQDMSA-N |
Product Description
Applications: 5-Fluorodeoxyuridine monophosphate is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both catalog item and custom-synthesis project (mg to ton scale), with full analytical documentation (COA, MSDS, HPLC, NMR, MS).
5-Fluorodeoxyuridine monophosphate is a pharmaceutical intermediate identified by CAS number 134-46-3 and the molecular formula C9H12FN2O8P and a molecular weight of 326.03 g/mol. Synonyms include FdUMP and 5-Fluoro-dUMP.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of 5-Fluorodeoxyuridine monophosphate
Property Insights of 5-Fluorodeoxyuridine monophosphate
The XLogP value of -2.8 indicates that 5-Fluorodeoxyuridine monophosphate is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. The TPSA of 146.0 Ų indicates high polarity, suggesting 5-Fluorodeoxyuridine monophosphate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 5-Fluorodeoxyuridine monophosphate has 4 hydrogen bond donor(s) and 9 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Fluorodeoxyuridine monophosphate?
The CAS number of 5-Fluorodeoxyuridine monophosphate is 134-46-3.
What is the molecular formula of 5-Fluorodeoxyuridine monophosphate?
The molecular formula of 5-Fluorodeoxyuridine monophosphate is C9H12FN2O8P.
What is the molecular weight of 5-Fluorodeoxyuridine monophosphate?
The molecular weight of 5-Fluorodeoxyuridine monophosphate is 326.03152 g/mol.
What are the applications of 5-Fluorodeoxyuridine monophosphate?
5-Fluorodeoxyuridine monophosphate is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. Available from CoreyChem as both...
Where can I buy 5-Fluorodeoxyuridine monophosphate?
You can request a quote for 5-Fluorodeoxyuridine monophosphate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Fluorodeoxyuridine monophosphate?
Yes, CoreyChem provides custom synthesis services for 5-Fluorodeoxyuridine monophosphate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.