3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate
TL;DR: 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate (CAS 134250-28-5) is a chemical compound with molecular formula C18H29N6O8P and molecular weight 488.17844 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
methyl 5-[[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-ethoxyphosphoryl]amino]pentanoate
Also Known As: 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate, methyl 5-[[[(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy-ethoxy-phosphoryl]amino]pentanoate, Thymidine, 3'-azido-3'-deoxy-, 5'-[ethyl (5-methoxy-5-oxopentyl)phosphoramidate],-, 1-(3-Azido-2,3-dideoxy-5-O-{ethoxy[(5-methoxy-5-oxopentyl)amino]phosphoryl}-beta-D-erythro-pentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one, 1-(3-Azido-2,3-dideoxy-5-O-{ethoxy[(5-methoxy-5-oxopentyl)amino]phosphoryl}pentofuranosyl)-4-hydroxy-5-methylpyrimidin-2(1H)-one
Technical Specifications
| Molecular Formula | C18H29N6O8P |
| Molecular Weight | 488.17844 g/mol |
| XLogP | 0.7 |
| Topological Polar Surface Area (TPSA) | 147.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 14 |
| Exact Mass | 488.17844 Da |
| Heavy Atoms | 33 |
| Complexity | 861.0 |
| SMILES | CCOP(=O)(NCCCCC(=O)OC)OC[C@@H]1[C@H](C[C@@H](O1)N2C=C(C(=O)NC2=O)C)N=[N+]=[N-] |
| InChIKey | OTXHCJAMPYCYNJ-SFBRXVQLSA-N |
Chemical Property Profile of 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate
Property Insights of 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate
The XLogP value of 0.7 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate. The TPSA of 147.0 Ų indicates high polarity, suggesting 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate has 2 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate?
The CAS number of 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate is 134250-28-5.
What is the molecular formula of 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate?
The molecular formula of 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate is C18H29N6O8P.
What is the molecular weight of 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate?
The molecular weight of 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate is 488.17844 g/mol.
Where can I buy 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate?
You can request a quote for 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate?
Yes, CoreyChem provides custom synthesis services for 3'-Azido-3'-deoxythymidine-5'-(ethyl methoxy-5-aminovaleryl)phosphoramidate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.