4-Hydroxyretinoic acid
TL;DR: 4-Hydroxyretinoic acid (CAS 1346606-78-7) is a chemical compound with molecular formula C20H28O3 and molecular weight 316.20386 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2E,4E,6E,8E)-9-(3-hydroxy-2,6,6-trimethylcyclohexen-1-yl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid
Also Known As: 4-Hydroxyretinoic acid, rac all-trans, 4-hydroxy-all-trans-retinoic acid, 4-OH-retinoate, all-trans-4-hydroxyretinoic acid
Technical Specifications
| Molecular Formula | C20H28O3 |
| Molecular Weight | 316.20386 g/mol |
| XLogP | 4.5 |
| Topological Polar Surface Area (TPSA) | 57.5 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 316.20386 Da |
| Heavy Atoms | 23 |
| Complexity | 598.0 |
| SMILES | CC1=C(C(CCC1O)(C)C)/C=C/C(=C/C=C/C(=C/C(=O)O)/C)/C |
| InChIKey | KGUMXGDKXYTTEY-FRCNGJHJSA-N |
Chemical Property Profile of 4-Hydroxyretinoic acid
Property Insights of 4-Hydroxyretinoic acid
The XLogP value of 4.5 indicates that 4-Hydroxyretinoic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.5 Ų, 4-Hydroxyretinoic acid exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-Hydroxyretinoic acid has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 4-Hydroxyretinoic acid?
The CAS number of 4-Hydroxyretinoic acid is 1346606-78-7.
What is the molecular formula of 4-Hydroxyretinoic acid?
The molecular formula of 4-Hydroxyretinoic acid is C20H28O3.
What is the molecular weight of 4-Hydroxyretinoic acid?
The molecular weight of 4-Hydroxyretinoic acid is 316.20386 g/mol.
Where can I buy 4-Hydroxyretinoic acid?
You can request a quote for 4-Hydroxyretinoic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 4-Hydroxyretinoic acid?
Yes, CoreyChem provides custom synthesis services for 4-Hydroxyretinoic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.