5-Chloro-2'-deoxy-4'-thiouridine
TL;DR: 5-Chloro-2'-deoxy-4'-thiouridine (CAS 134700-02-0) is a chemical compound with molecular formula C9H11ClN2O4S and molecular weight 278.01282 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione
Also Known As: 5-Chloro-2'-deoxy-4'-thiouridine, uridine, 5-chloro-2'-deoxy-4'-thio-, 5-chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione, 5-chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl]pyrimidine-2,4-dione
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H11ClN2O4S |
| Molecular Weight | 278.01282 g/mol |
| XLogP | 0.3 |
| Topological Polar Surface Area (TPSA) | 115.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 278.01282 Da |
| Heavy Atoms | 17 |
| Complexity | 389.0 |
| SMILES | C1[C@@H]([C@H](S[C@H]1N2C=C(C(=O)NC2=O)Cl)CO)O |
| InChIKey | GYSHEQSCWHBMQF-RRKCRQDMSA-N |
Chemical Property Profile of 5-Chloro-2'-deoxy-4'-thiouridine
Property Insights of 5-Chloro-2'-deoxy-4'-thiouridine
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 5-Chloro-2'-deoxy-4'-thiouridine. The TPSA of 115.0 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-Chloro-2'-deoxy-4'-thiouridine. Following Lipinski's Rule of Five, 5-Chloro-2'-deoxy-4'-thiouridine has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Chloro-2'-deoxy-4'-thiouridine?
The CAS number of 5-Chloro-2'-deoxy-4'-thiouridine is 134700-02-0.
What is the molecular formula of 5-Chloro-2'-deoxy-4'-thiouridine?
The molecular formula of 5-Chloro-2'-deoxy-4'-thiouridine is C9H11ClN2O4S.
What is the molecular weight of 5-Chloro-2'-deoxy-4'-thiouridine?
The molecular weight of 5-Chloro-2'-deoxy-4'-thiouridine is 278.01282 g/mol.
Where can I buy 5-Chloro-2'-deoxy-4'-thiouridine?
You can request a quote for 5-Chloro-2'-deoxy-4'-thiouridine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Chloro-2'-deoxy-4'-thiouridine?
Yes, CoreyChem provides custom synthesis services for 5-Chloro-2'-deoxy-4'-thiouridine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.