5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine
TL;DR: 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine (CAS 134881-09-7) is a chemical compound with molecular formula C5H4ClF3N2S and molecular weight 218.99242 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
5-chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine
Also Known As: 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine, 5-chloro-N-methyl-4-(trifluoromethyl)-1,3-thiazol-2-amine, 5-Chloro-N-(~2~H_3_)methyl-4-(trifluoromethyl)-1,3-thiazol-2(3H)-imine
Technical Specifications
| Molecular Formula | C5H4ClF3N2S |
| Molecular Weight | 218.99242 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 53.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 1 |
| Exact Mass | 218.99242 Da |
| Heavy Atoms | 12 |
| Complexity | 165.0 |
| SMILES | [2H]C([2H])([2H])NC1=NC(=C(S1)Cl)C(F)(F)F |
| InChIKey | QTRIJXYISPTCHZ-FIBGUPNXSA-N |
Chemical Property Profile of 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine
Property Insights of 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine
The XLogP value of 3.2 indicates that 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 53.2 Ų, 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine?
The CAS number of 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine is 134881-09-7.
What is the molecular formula of 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine?
The molecular formula of 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine is C5H4ClF3N2S.
What is the molecular weight of 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine?
The molecular weight of 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine is 218.99242 g/mol.
Where can I buy 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine?
You can request a quote for 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine?
Yes, CoreyChem provides custom synthesis services for 5-Chloro-N-(trideuteriomethyl)-4-(trifluoromethyl)-1,3-thiazol-2-amine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.