Methyclothiazide
TL;DR: Methyclothiazide (CAS 135-07-9) is a chemical compound with molecular formula C9H11Cl2N3O4S2 and molecular weight 358.95682 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
6-chloro-3-(chloromethyl)-2-methyl-1,1-dioxo-3,4-dihydro-1λ6,2,4-benzothiadiazine-7-sulfonamide
Also Known As: methyclothiazide, Enduron, Aquatensen, Methyclothiazid, Duretic
Application Areas
Top 5 of 12 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C9H11Cl2N3O4S2 |
| Molecular Weight | 358.95682 g/mol |
| XLogP | 1.4 |
| Topological Polar Surface Area (TPSA) | 126.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 358.95682 Da |
| Heavy Atoms | 20 |
| Complexity | 571.0 |
| Melting Point | 225 |
| Solubility | 11.2 |
| SMILES | CN1C(NC2=CC(=C(C=C2S1(=O)=O)S(=O)(=O)N)Cl)CCl |
| InChIKey | CESYKOGBSMNBPD-UHFFFAOYSA-N |
Chemical Property Profile of Methyclothiazide
Property Insights of Methyclothiazide
The XLogP value of 1.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Methyclothiazide. The TPSA of 126.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Methyclothiazide. Following Lipinski's Rule of Five, Methyclothiazide has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Methyclothiazide?
The CAS number of Methyclothiazide is 135-07-9.
What is the molecular formula of Methyclothiazide?
The molecular formula of Methyclothiazide is C9H11Cl2N3O4S2.
What is the molecular weight of Methyclothiazide?
The molecular weight of Methyclothiazide is 358.95682 g/mol.
Where can I buy Methyclothiazide?
You can request a quote for Methyclothiazide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Methyclothiazide?
Yes, CoreyChem provides custom synthesis services for Methyclothiazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.