Hydroflumethiazide
TL;DR: Hydroflumethiazide (CAS 135-09-1) is a chemical compound with molecular formula C8H8F3N3O4S2 and molecular weight 330.99084 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
Also Known As: hydroflumethiazide, Diuredemina, Glomerulin, Diucardin, Saluron
Application Areas
Top 5 of 14 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C8H8F3N3O4S2 |
| Molecular Weight | 330.99084 g/mol |
| XLogP | 0.4 |
| Topological Polar Surface Area (TPSA) | 135.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 10 |
| Rotatable Bonds | 1 |
| Exact Mass | 330.99084 Da |
| Heavy Atoms | 20 |
| Complexity | 578.0 |
| Melting Point | 272-273 |
| Solubility | 300 |
| SMILES | C1NC2=C(C=C(C(=C2)C(F)(F)F)S(=O)(=O)N)S(=O)(=O)N1 |
| InChIKey | DMDGGSIALPNSEE-UHFFFAOYSA-N |
Product Description
Applications: Hydroflumethiazide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Hydroflumethiazide (CAS 135-09-1) with custom synthesis available from milligram to multi-kilogram scale, supported by COA, MSDS, and HPLC/NMR/MS documentation.
A pharmaceutical intermediate supplied by CoreyChem, Hydroflumethiazide (CAS 135-09-1) has the molecular formula C8H8F3N3O4S2 and a molecular weight of 330.99 g/mol. Reported properties include a solubility: 300. It is also known as hydroflumethiazide and Diuredemina.
Custom synthesis and full analytical documentation (COA/MSDS) are available from CoreyChem. Request a quotation with your required quantity and purity for current lead time and pricing.
Chemical Property Profile of Hydroflumethiazide
Property Insights of Hydroflumethiazide
The XLogP value of 0.4 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Hydroflumethiazide. The TPSA of 135.0 Ų falls within the moderate polarity range, balancing permeability and solubility for Hydroflumethiazide. Following Lipinski's Rule of Five, Hydroflumethiazide has 3 hydrogen bond donor(s) and 10 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Hydroflumethiazide?
The CAS number of Hydroflumethiazide is 135-09-1.
What is the molecular formula of Hydroflumethiazide?
The molecular formula of Hydroflumethiazide is C8H8F3N3O4S2.
What is the molecular weight of Hydroflumethiazide?
The molecular weight of Hydroflumethiazide is 330.99084 g/mol.
What are the applications of Hydroflumethiazide?
Hydroflumethiazide is used in pharmaceutical synthesis routes and API production, as well as heterocycle construction in medicinal chemistry and agrochemical discovery. It commonly serves as a versatile building block for organic synthesis. CoreyChem supplies Hydroflumethiazide (CAS 135-09-1)...
Where can I buy Hydroflumethiazide?
You can request a quote for Hydroflumethiazide directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Hydroflumethiazide?
Yes, CoreyChem provides custom synthesis services for Hydroflumethiazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.