3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one
TL;DR: 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one (CAS 1351406-38-6) is a chemical compound with molecular formula C17H18N4O and molecular weight 294.14807 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
3-phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one
Also Known As: 3-PHENYL-1-(4-PYRIMIDIN-2-YLPIPERAZINYL)PROP-2-EN-1-ONE, 3-phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one, (E)-3-phenyl-1-[4-(2-pyrimidinyl)piperazino]-2-propen-1-one, 3-phenyl-1-(4-(pyrimidin-2-yl) piperazin-1-yl)-prop-2-en-1-one, 3-phenyl-1-[4-(pyrimidin-2-yl)piperazin-1-yl]prop-2-en-1-one
Technical Specifications
| Molecular Formula | C17H18N4O |
| Molecular Weight | 294.14807 g/mol |
| XLogP | 2.0 |
| Topological Polar Surface Area (TPSA) | 49.3 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 294.14807 Da |
| Heavy Atoms | 22 |
| Complexity | 378.0 |
| SMILES | C1CN(CCN1C2=NC=CC=N2)C(=O)C=CC3=CC=CC=C3 |
| InChIKey | XCGMDDSRZZXNOE-UHFFFAOYSA-N |
Chemical Property Profile of 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one
Property Insights of 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one
The XLogP value of 2.0 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one. With a topological polar surface area (TPSA) of 49.3 Ų, 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one has 0 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one?
The CAS number of 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one is 1351406-38-6.
What is the molecular formula of 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one?
The molecular formula of 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one is C17H18N4O.
What is the molecular weight of 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one?
The molecular weight of 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one is 294.14807 g/mol.
Where can I buy 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one?
You can request a quote for 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one?
Yes, CoreyChem provides custom synthesis services for 3-Phenyl-1-(4-pyrimidin-2-ylpiperazin-1-yl)prop-2-en-1-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.