TL;DR: N'-[(3Z)-1-ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]pyridine-2-carbohydrazide (CAS 1351440-74-8) is a chemical compound with molecular formula C16H14N4O2 and molecular weight 294.11166 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-(1-ethyl-2-hydroxyindol-3-yl)iminopyridine-2-carboxamide
Also Known As: (Z)-N'-(1-ethyl-2-oxoindolin-3-ylidene)picolinohydrazide, N-[(1-ethyl-2-oxoindol-3-ylidene)amino]pyridine-2-carboxamide, N-[(E)-(1-ethyl-2-oxoindol-3-ylidene)amino]pyridine-2-carboxamide, N-[(Z)-(1-ethyl-2-oxoindol-3-ylidene)amino]pyridine-2-carboxamide, N'-(1-ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-2-pyridinecarbohydrazide
| Molecular Formula | C16H14N4O2 |
| Molecular Weight | 294.11166 g/mol |
| XLogP | 3.2 |
| Topological Polar Surface Area (TPSA) | 79.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 3 |
| Exact Mass | 294.11166 Da |
| Heavy Atoms | 22 |
| Complexity | 428.0 |
| SMILES | CCN1C2=CC=CC=C2C(=C1O)N=NC(=O)C3=CC=CC=N3 |
| InChIKey | LHXRTPTUUNYOAF-UHFFFAOYSA-N |
The XLogP value of 3.2 indicates that N'-[(3Z)-1-ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]pyridine-2-carbohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 79.8 Ų falls within the moderate polarity range, balancing permeability and solubility for N'-[(3Z)-1-ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]pyridine-2-carbohydrazide. Following Lipinski's Rule of Five, N'-[(3Z)-1-ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]pyridine-2-carbohydrazide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of N'-[(3Z)-1-ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]pyridine-2-carbohydrazide is 1351440-74-8.
The molecular formula of N'-[(3Z)-1-ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]pyridine-2-carbohydrazide is C16H14N4O2.
The molecular weight of N'-[(3Z)-1-ethyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene]pyridine-2-carbohydrazide is 294.11166 g/mol.
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