TL;DR: 4-(2-(4-(Dimethylamino)phenyl)vinyl)-8-quinolinol (CAS 1351448-85-5) is a chemical compound with molecular formula C19H18N2O and molecular weight 290.1419 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-[(E)-2-[4-(dimethylamino)phenyl]ethenyl]quinolin-8-ol
Also Known As: 4-(4-(Dimethylamino)styryl)quinolin-8-ol, 4-(2-(4-(Dimethylamino)phenyl)vinyl)-8-quinolinol, 8-Quinolinol, 4-[p-(dimethylamino)styryl]-, 8-Quinolinol,4-[2-[4-(dimethylamino)phenyl]ethenyl]-, AT-051/43421298
| Molecular Formula | C19H18N2O |
| Molecular Weight | 290.1419 g/mol |
| XLogP | 4.4 |
| Topological Polar Surface Area (TPSA) | 36.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 290.1419 Da |
| Heavy Atoms | 22 |
| Complexity | 374.0 |
| SMILES | CN(C)C1=CC=C(C=C1)/C=C/C2=C3C=CC=C(C3=NC=C2)O |
| InChIKey | OSSROFZTGSSYNR-RMKNXTFCSA-N |
The XLogP value of 4.4 indicates that 4-(2-(4-(Dimethylamino)phenyl)vinyl)-8-quinolinol is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 36.4 Ų, 4-(2-(4-(Dimethylamino)phenyl)vinyl)-8-quinolinol exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(2-(4-(Dimethylamino)phenyl)vinyl)-8-quinolinol has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
The CAS number of 4-(2-(4-(Dimethylamino)phenyl)vinyl)-8-quinolinol is 1351448-85-5.
The molecular formula of 4-(2-(4-(Dimethylamino)phenyl)vinyl)-8-quinolinol is C19H18N2O.
The molecular weight of 4-(2-(4-(Dimethylamino)phenyl)vinyl)-8-quinolinol is 290.1419 g/mol.
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