2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane
TL;DR: 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane (CAS 135245-06-6) is a chemical compound with molecular formula C6H4F6O2 and molecular weight 222.01155 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
4-methylidene-2,2-bis(trifluoromethyl)-1,3-dioxolane
Also Known As: 4-Methylene-2,2-bis(trifluoromethyl)-1,3-dioxolane, 4-methylidene-2,2-bis(trifluoromethyl)-1,3-dioxolane, 2,2-bis(trifluoromethyl)-4-methylene-1,3-dioxolane
Technical Specifications
| Molecular Formula | C6H4F6O2 |
| Molecular Weight | 222.01155 g/mol |
| XLogP | 2.5 |
| Topological Polar Surface Area (TPSA) | 18.5 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 0 |
| Exact Mass | 222.01155 Da |
| Heavy Atoms | 14 |
| Complexity | 238.0 |
| SMILES | C=C1COC(O1)(C(F)(F)F)C(F)(F)F |
| InChIKey | NISZWNSSJAXFEE-UHFFFAOYSA-N |
Chemical Property Profile of 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane
Property Insights of 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane. With a topological polar surface area (TPSA) of 18.5 Ų, 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane has 0 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane?
The CAS number of 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane is 135245-06-6.
What is the molecular formula of 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane?
The molecular formula of 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane is C6H4F6O2.
What is the molecular weight of 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane?
The molecular weight of 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane is 222.01155 g/mol.
Where can I buy 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane?
You can request a quote for 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane?
Yes, CoreyChem provides custom synthesis services for 2,2-Bis(trifluoromethyl)-4-methylene-1,3-dioxolane and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.