10,11-Methylenedioxy-20-camptothecin
TL;DR: 10,11-Methylenedioxy-20-camptothecin (CAS 135415-73-5) is a chemical compound with molecular formula C21H16N2O6 and molecular weight 392.10083 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(5S)-5-ethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.04,9.015,23.017,21]tetracosa-1(13),2,4(9),14,16,21,23-heptaene-6,10-dione
Also Known As: Mdo-cpt, FL118, 10,11-Methylenedioxycamptothecin, 10,11-Methylenedioxy-20S-camptothecin, ethyl(hydroxy)[?]dione
Technical Specifications
| Molecular Formula | C21H16N2O6 |
| Molecular Weight | 392.10083 g/mol |
| XLogP | 0.8 |
| Topological Polar Surface Area (TPSA) | 98.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 1 |
| Exact Mass | 392.10083 Da |
| Heavy Atoms | 29 |
| Complexity | 852.0 |
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=C6C(=CC5=C4)OCO6)O |
| InChIKey | RPFYDENHBPRCTN-NRFANRHFSA-N |
Chemical Property Profile of 10,11-Methylenedioxy-20-camptothecin
Property Insights of 10,11-Methylenedioxy-20-camptothecin
The XLogP value of 0.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 10,11-Methylenedioxy-20-camptothecin. The TPSA of 98.2 Ų falls within the moderate polarity range, balancing permeability and solubility for 10,11-Methylenedioxy-20-camptothecin. Following Lipinski's Rule of Five, 10,11-Methylenedioxy-20-camptothecin has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 10,11-Methylenedioxy-20-camptothecin?
The CAS number of 10,11-Methylenedioxy-20-camptothecin is 135415-73-5.
What is the molecular formula of 10,11-Methylenedioxy-20-camptothecin?
The molecular formula of 10,11-Methylenedioxy-20-camptothecin is C21H16N2O6.
What is the molecular weight of 10,11-Methylenedioxy-20-camptothecin?
The molecular weight of 10,11-Methylenedioxy-20-camptothecin is 392.10083 g/mol.
Where can I buy 10,11-Methylenedioxy-20-camptothecin?
You can request a quote for 10,11-Methylenedioxy-20-camptothecin directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 10,11-Methylenedioxy-20-camptothecin?
Yes, CoreyChem provides custom synthesis services for 10,11-Methylenedioxy-20-camptothecin and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.