10-Propargyl-5-deazaaminopterin analog of folic acid
TL;DR: 10-Propargyl-5-deazaaminopterin analog of folic acid (CAS 135423-84-6) is a chemical compound with molecular formula C23H23N7O5 and molecular weight 477.17606 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-2-[[4-[(2,4-diaminopyrido[2,3-d]pyrimidin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid
Also Known As: 10-Pdapt, 10-propargyl-5-deazaaminopterin, 10-Propargyl-5-deazaaminopterin analog of folic acid, (2S)-2-[[4-[(2,4-diaminopyrido[2,3-d]pyrimidin-6-yl)methyl-prop-2-ynylamino]benzoyl]amino]pentanedioic acid, (2S)-2-({4-[({2,4-diaminopyrido[2,3-d]pyrimidin-6-yl}methyl)(prop-2-yn-1-yl)amino]phenyl}formamido)pentanedioic acid
Technical Specifications
| Molecular Formula | C23H23N7O5 |
| Molecular Weight | 477.17606 g/mol |
| XLogP | 0.6 |
| Topological Polar Surface Area (TPSA) | 198.0 Ų |
| Hydrogen Bond Donors | 5 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 10 |
| Exact Mass | 477.17606 Da |
| Heavy Atoms | 35 |
| Complexity | 809.0 |
| SMILES | C#CCN(CC1=CC2=C(N=C(N=C2N=C1)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O |
| InChIKey | IOYMKUPOYSMDNI-KRWDZBQOSA-N |
Chemical Property Profile of 10-Propargyl-5-deazaaminopterin analog of folic acid
Property Insights of 10-Propargyl-5-deazaaminopterin analog of folic acid
The XLogP value of 0.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 10-Propargyl-5-deazaaminopterin analog of folic acid. The TPSA of 198.0 Ų indicates high polarity, suggesting 10-Propargyl-5-deazaaminopterin analog of folic acid may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 10-Propargyl-5-deazaaminopterin analog of folic acid has 5 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
What is the CAS number of 10-Propargyl-5-deazaaminopterin analog of folic acid?
The CAS number of 10-Propargyl-5-deazaaminopterin analog of folic acid is 135423-84-6.
What is the molecular formula of 10-Propargyl-5-deazaaminopterin analog of folic acid?
The molecular formula of 10-Propargyl-5-deazaaminopterin analog of folic acid is C23H23N7O5.
What is the molecular weight of 10-Propargyl-5-deazaaminopterin analog of folic acid?
The molecular weight of 10-Propargyl-5-deazaaminopterin analog of folic acid is 477.17606 g/mol.
Where can I buy 10-Propargyl-5-deazaaminopterin analog of folic acid?
You can request a quote for 10-Propargyl-5-deazaaminopterin analog of folic acid directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 10-Propargyl-5-deazaaminopterin analog of folic acid?
Yes, CoreyChem provides custom synthesis services for 10-Propargyl-5-deazaaminopterin analog of folic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.