TL;DR: Amlodipine Maleate (CAS 1357024-06-6) is a chemical compound with molecular formula C24H29ClN2O9 and molecular weight 524.1561 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(Z)-but-2-enedioic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Also Known As: Amlodipine maleate, Amvaz, Amlodipine (maleate), AmlodipineMaleate, Amlodipine maleate [USAN]
| Molecular Formula | C24H29ClN2O9 |
| Molecular Weight | 524.1561 g/mol |
| XLogP | 1.9781 |
| Topological Polar Surface Area (TPSA) | 174.0 Ų |
| Hydrogen Bond Donors | 4 |
| Hydrogen Bond Acceptors | 11 |
| Rotatable Bonds | 12 |
| Exact Mass | 524.1561 Da |
| Heavy Atoms | 36 |
| Complexity | 765.0 |
| SMILES | CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C(=C\C(=O)O)\C(=O)O |
| InChIKey | TZNOWAJJWCGILX-BTJKTKAUSA-N |
The XLogP value of 1.9781 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Amlodipine Maleate. The TPSA of 174.0 Ų indicates high polarity, suggesting Amlodipine Maleate may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, Amlodipine Maleate has 4 hydrogen bond donor(s) and 11 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
The CAS number of Amlodipine Maleate is 1357024-06-6.
The molecular formula of Amlodipine Maleate is C24H29ClN2O9.
The molecular weight of Amlodipine Maleate is 524.1561 g/mol.
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