Koumine
TL;DR: Koumine (CAS 1358-76-5) is a chemical compound with molecular formula C20H22N2O and molecular weight 306.17322 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
15-ethenyl-13-methyl-19-oxa-3,13-diazahexacyclo[14.3.1.02,10.04,9.010,15.012,17]icosa-2,4,6,8-tetraene
Also Known As: Koumine, 4CN-1554, 15-ethenyl-13-methyl-19-oxa-3,13-diazahexacyclo[14.3.1.02,10.04,9.010,15.012,17]icosa-2,4,6,8-tetraene, 7,20(2H,19H)-Cyclovobasan, 1,2,18,19-tetradehydro-3,17-epoxy-, (3R,7alpha,20alpha)-, (1R,10R,12S,15S,16R,17S)-15-ethenyl-13-methyl-19-oxa-3,13-diazahexacyclo[14.3.1.0^{2,10.0^{4,9.0^{10,15.0^{12,17]icosa-2,4,6,8-tetraene
Technical Specifications
| Molecular Formula | C20H22N2O |
| Molecular Weight | 306.17322 g/mol |
| XLogP | 2.5 |
| Topological Polar Surface Area (TPSA) | 24.8 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 306.17322 Da |
| Heavy Atoms | 23 |
| Complexity | 615.0 |
| SMILES | CN1CC2(C3CC4C5=NC6=CC=CC=C6C52CC1C3CO4)C=C |
| InChIKey | VTLYEMHGPMGUOT-UHFFFAOYSA-N |
Chemical Property Profile of Koumine
Property Insights of Koumine
The XLogP value of 2.5 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Koumine. With a topological polar surface area (TPSA) of 24.8 Ų, Koumine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Koumine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Koumine?
The CAS number of Koumine is 1358-76-5.
What is the molecular formula of Koumine?
The molecular formula of Koumine is C20H22N2O.
What is the molecular weight of Koumine?
The molecular weight of Koumine is 306.17322 g/mol.
Where can I buy Koumine?
You can request a quote for Koumine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Koumine?
Yes, CoreyChem provides custom synthesis services for Koumine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.