A 65282
TL;DR: A 65282 (CAS 135906-72-8) is a chemical compound with molecular formula C17H16F2N4O2S and molecular weight 378.0962 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
7-(3-aminopyrrolidin-1-yl)-9-cyclopropyl-6,8-difluoro-[1,2]thiazolo[5,4-b]quinoline-3,4-dione
Also Known As: A 65282, A-65282, 7-(3-aminopyrrolidin-1-yl)-9-cyclopropyl-6,8-difluoro-[1,2]thiazolo[5,4-b]quinoline-3,4-dione, Isothiazolo(5,4-b)quinoline-3,4(2H,9H)-dione, 7-(3-amino-1-pyrrolidinyl)-9-cyclopropyl-6,8-difluoro-, 6,8-Difluoro-7-(3-amino-1-pyrrolidinyl)-9-cyclopropylisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione
Application Areas
Top 5 of 3 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C17H16F2N4O2S |
| Molecular Weight | 378.0962 g/mol |
| XLogP | 1.6 |
| Topological Polar Surface Area (TPSA) | 104.0 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 2 |
| Exact Mass | 378.0962 Da |
| Heavy Atoms | 26 |
| Complexity | 700.0 |
| SMILES | C1CC1N2C3=C(C(=C(C=C3C(=O)C4=C2SNC4=O)F)N5CCC(C5)N)F |
| InChIKey | NUOJLJDXSSHQBA-UHFFFAOYSA-N |
Chemical Property Profile of A 65282
Property Insights of A 65282
The XLogP value of 1.6 suggests moderate lipophilicity, balancing water solubility and membrane permeability for A 65282. The TPSA of 104.0 Ų falls within the moderate polarity range, balancing permeability and solubility for A 65282. Following Lipinski's Rule of Five, A 65282 has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of A 65282?
The CAS number of A 65282 is 135906-72-8.
What is the molecular formula of A 65282?
The molecular formula of A 65282 is C17H16F2N4O2S.
What is the molecular weight of A 65282?
The molecular weight of A 65282 is 378.0962 g/mol.
Where can I buy A 65282?
You can request a quote for A 65282 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for A 65282?
Yes, CoreyChem provides custom synthesis services for A 65282 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.