SKI 178
TL;DR: SKI 178 (CAS 1359880-51-5) is a chemical compound with molecular formula C21H22N4O4 and molecular weight 394.1641 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
N-[(E)-1-(3,4-dimethoxyphenyl)ethylideneamino]-3-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
Also Known As: SKI 178, EX-A8537, N'-(1-(3,4-Dimethoxyphenyl)ethylidene)-3-(4-methoxyphenyl)-1H-pyrazole-5-carbohydrazide, SKI-178; SKI 178; SKI178, EC-000.2507
Technical Specifications
| Molecular Formula | C21H22N4O4 |
| Molecular Weight | 394.1641 g/mol |
| XLogP | 3.3 |
| Topological Polar Surface Area (TPSA) | 97.8 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 7 |
| Exact Mass | 394.1641 Da |
| Heavy Atoms | 29 |
| Complexity | 565.0 |
| SMILES | C/C(=N\NC(=O)C1=CC(=NN1)C2=CC=C(C=C2)OC)/C3=CC(=C(C=C3)OC)OC |
| InChIKey | GMFUWEBOUKIKRP-LPYMAVHISA-N |
Chemical Property Profile of SKI 178
Property Insights of SKI 178
The XLogP value of 3.3 indicates that SKI 178 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 97.8 Ų falls within the moderate polarity range, balancing permeability and solubility for SKI 178. Following Lipinski's Rule of Five, SKI 178 has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of SKI 178?
The CAS number of SKI 178 is 1359880-51-5.
What is the molecular formula of SKI 178?
The molecular formula of SKI 178 is C21H22N4O4.
What is the molecular weight of SKI 178?
The molecular weight of SKI 178 is 394.1641 g/mol.
Where can I buy SKI 178?
You can request a quote for SKI 178 directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for SKI 178?
Yes, CoreyChem provides custom synthesis services for SKI 178 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.