Nexopamil
TL;DR: Nexopamil (CAS 136033-49-3) is a chemical compound with molecular formula C24H40N2O3 and molecular weight 404.3039 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(2S)-5-[hexyl(methyl)amino]-2-propan-2-yl-2-(3,4,5-trimethoxyphenyl)pentanenitrile
Also Known As: Nexopamil, nexopamilo, nexopamilum, Nexopamil [INN], nexopamil[inn]
Application Areas
Top 5 of 5 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C24H40N2O3 |
| Molecular Weight | 404.3039 g/mol |
| XLogP | 4.2 |
| Topological Polar Surface Area (TPSA) | 54.7 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 14 |
| Exact Mass | 404.3039 Da |
| Heavy Atoms | 29 |
| Complexity | 476.0 |
| SMILES | CCCCCCN(C)CCC[C@@](C#N)(C1=CC(=C(C(=C1)OC)OC)OC)C(C)C |
| InChIKey | SKDZEFVVFACNLS-DEOSSOPVSA-N |
Chemical Property Profile of Nexopamil
Property Insights of Nexopamil
The XLogP value of 4.2 indicates that Nexopamil is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 54.7 Ų, Nexopamil exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nexopamil has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Nexopamil?
The CAS number of Nexopamil is 136033-49-3.
What is the molecular formula of Nexopamil?
The molecular formula of Nexopamil is C24H40N2O3.
What is the molecular weight of Nexopamil?
The molecular weight of Nexopamil is 404.3039 g/mol.
Where can I buy Nexopamil?
You can request a quote for Nexopamil directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Nexopamil?
Yes, CoreyChem provides custom synthesis services for Nexopamil and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.