Piperazine deriv.
TL;DR: Piperazine deriv. (CAS 136817-55-5) is a chemical compound with molecular formula C21H26N6O and molecular weight 378.2168 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
(5-amino-1H-indol-2-yl)-[4-[3-(propan-2-ylamino)-2-pyridinyl]piperazin-1-yl]methanone
Also Known As: Piperazine deriv., 5- or 6-Substituted Indole BHAP analogue 8, Piperazine, 1-((5-amino-1H-indol-2-yl)carbonyl)-4-(3-((1-methylethyl)amino)-2-pyridinyl)-, N-[5-Amino-2-indolcarbonyl]-N'-[3-(isopropylamino)-2-pyridinyl]piperazine, (5-Amino-1H-indol-2-yl)(4-{3-[(propan-2-yl)amino]pyridin-2-yl}piperazin-1-yl)methanone
Application Areas
Top 5 of 2 IPC patent classification(s) from the SureChEMBL global patent database.
Technical Specifications
| Molecular Formula | C21H26N6O |
| Molecular Weight | 378.2168 g/mol |
| XLogP | 2.8 |
| Topological Polar Surface Area (TPSA) | 90.3 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 378.2168 Da |
| Heavy Atoms | 28 |
| Complexity | 535.0 |
| SMILES | CC(C)NC1=C(N=CC=C1)N2CCN(CC2)C(=O)C3=CC4=C(N3)C=CC(=C4)N |
| InChIKey | IYNANDLXMWZGBU-UHFFFAOYSA-N |
Chemical Property Profile of Piperazine deriv.
Property Insights of Piperazine deriv.
The XLogP value of 2.8 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Piperazine deriv.. The TPSA of 90.3 Ų falls within the moderate polarity range, balancing permeability and solubility for Piperazine deriv.. Following Lipinski's Rule of Five, Piperazine deriv. has 3 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of Piperazine deriv.?
The CAS number of Piperazine deriv. is 136817-55-5.
What is the molecular formula of Piperazine deriv.?
The molecular formula of Piperazine deriv. is C21H26N6O.
What is the molecular weight of Piperazine deriv.?
The molecular weight of Piperazine deriv. is 378.2168 g/mol.
Where can I buy Piperazine deriv.?
You can request a quote for Piperazine deriv. directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for Piperazine deriv.?
Yes, CoreyChem provides custom synthesis services for Piperazine deriv. and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.