![1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile structure](/static/products/1368/136819-62-0.webp)
1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile
TL;DR: 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile (CAS 136819-62-0) is a chemical compound with molecular formula C15H16N2 and molecular weight 224.13135 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile
Also Known As: 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile, 1-amino-3,4-dihydrospiro[naphthalene-3,1'-cyclopentane]-2-carbonitrile, AE-848/31946014, 4'-amino-1'H-spiro[cyclopentane-1,2'-naphthalene]-3'-carbonitrile, 4-amino-3-cyano-1,2-dihydrospiro(naphthalene-2,1'-cyclopentane)
Technical Specifications
| Molecular Formula | C15H16N2 |
| Molecular Weight | 224.13135 g/mol |
| XLogP | 3.8 |
| Topological Polar Surface Area (TPSA) | 49.8 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 0 |
| Exact Mass | 224.13135 Da |
| Heavy Atoms | 17 |
| Complexity | 392.0 |
| SMILES | C1CCC2(C1)CC3=CC=CC=C3C(=C2C#N)N |
| InChIKey | QTZRVRCBWOSGJG-UHFFFAOYSA-N |
Chemical Property Profile of 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile
Property Insights of 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile
The XLogP value of 3.8 indicates that 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 49.8 Ų, 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile?
The CAS number of 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile is 136819-62-0.
What is the molecular formula of 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile?
The molecular formula of 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile is C15H16N2.
What is the molecular weight of 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile?
The molecular weight of 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile is 224.13135 g/mol.
Where can I buy 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile?
You can request a quote for 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile?
Yes, CoreyChem provides custom synthesis services for 1-aminospiro[4H-naphthalene-3,1'-cyclopentane]-2-carbonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.