9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine
TL;DR: 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine (CAS 137719-31-4) is a chemical compound with molecular formula C10H14N6OS and molecular weight 266.09497 g/mol, supplied by CoreyChem (Career Henan Chemical Co., Ltd.) with ISO-certified quality and global shipping.
[(2S,5R)-5-(2,6-diaminopurin-9-yl)thiolan-2-yl]methanol
Also Known As: 2',3'-Dideoxy-4'-thionucleoside analog, 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine, 2-amino-2',3'-dideoxy-4'-thioadenosine, 2-Amino-2',3'-dideoxy-4'-thio-Adenosine, adenosine, 2-amino-2',3'-dideoxy-4'-thio-
Technical Specifications
| Molecular Formula | C10H14N6OS |
| Molecular Weight | 266.09497 g/mol |
| XLogP | 0.3 |
| Topological Polar Surface Area (TPSA) | 141.0 Ų |
| Hydrogen Bond Donors | 3 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 2 |
| Exact Mass | 266.09497 Da |
| Heavy Atoms | 18 |
| Complexity | 308.0 |
| SMILES | C1C[C@@H](S[C@@H]1CO)N2C=NC3=C(N=C(N=C32)N)N |
| InChIKey | XCBQEWWAIKYUCJ-NTSWFWBYSA-N |
Chemical Property Profile of 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine
Property Insights of 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine
The XLogP value of 0.3 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine. The TPSA of 141.0 Ų indicates high polarity, suggesting 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine may have limited membrane permeability but good aqueous solubility. Following Lipinski's Rule of Five, 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine has 3 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
What is the CAS number of 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine?
The CAS number of 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine is 137719-31-4.
What is the molecular formula of 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine?
The molecular formula of 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine is C10H14N6OS.
What is the molecular weight of 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine?
The molecular weight of 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine is 266.09497 g/mol.
Where can I buy 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine?
You can request a quote for 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine directly from CoreyChem. Contact us or email [email protected] for pricing and availability.
Does CoreyChem offer custom synthesis for 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine?
Yes, CoreyChem provides custom synthesis services for 9-(4-Thio-2,3-dideoxy-beta-D-ribofuranosyl)-2,6-diaminopurine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.